Phytochemical Screening, Antimicrobial and Antioxidant Activities of Aloe buettneri, Mitracarpus scaber and Hannoa undulata used in Togolese Cosmetopoeia

Background: Aloe buettneri, Mitracarpus scaber and Hannoa undulata are three plants species used in the Togolese traditional medicine to cure dermatosis. This study aims at assessing their anti-oxidant anti-microbial activities on acne-developing micro-organisms.
 Methods: Six micro-organisms including Cutibacterium acnes ATCC 6919, Pseudomonas aeruginosa 27853; Escherichia coli 25922; Klebsiella pneumoniae 700603; Staphylococcus aureus 29213; Candida albicans 35659 were used. Inhibition diameter was assessed using agar well diffusion method. Minimum inhibitory minimum microbicidal concentrations have been achieved through liquid dilution Anti-oxidant evaluated by DPPH antiradical scaving FRAP methods. Phytochemical screening also realized.
 Results: All microorganism’s strains tested, excepted coli, susceptible extracts 250 mg/mL assay with inhibition diameters ranging from 12.10 ± 0.07 18.20 0.10 mm. The MICs values comprised between 15.625 62.5 mg/mL, when MMCs ranged 31.25 125 mg/mL. At concentration of 500 µg/mL, scavenging properties radicals 49.20 0.15% for H. undulata, 41.29 0.51% A. 59.57 0.41% M. 87.22 0.03% Quercetin. For assay, effective (EC50) 977.44 1.13 µg/mL; 267.74 10.13 µg/mL and, 272.54 12.87 respectively while quercetin presented EC50 48.63 2.00 µg/mL. antimicrobial antioxidant these might be required presence polyphenols, tannins, flavonoids, triterpenes, saponoside alkaloids identified phytochemical screening.
 Conclusion: all potential natural candidates treating acne vulgaris.
 Keywords: scaber, activity, screening, Acne vulgaris